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Copper catalyzed five-component domino strategy for the synthesis of nicotinimidamides

Org. Biomol. Chem., 2021, Accepted ManuscriptDOI: 10.1039/D1OB00162K, PaperYu Zhao, Li Li, Zitong Zhou, Man Chen, Weiguang Yang, Hui LuoA library of medicinally and synthetically important nicotinimidamides were synthesized by a copper-catalyzed multicomponent domino reaction of oxime esters, terminal ynones, sulfonyl azides, aryl aldehydes and acetic ammonium. Its synthetic...The content of this RSS Feed (c) The Royal Society of Chemistry

Palladium-Catalyzed Carbonylative Cyclization of Benzyl Chlorides with Anthranils for the Synthesis of 3-Arylquinolin-2(1H)-ones

Org. Biomol. Chem., 2021, Accepted ManuscriptDOI: 10.1039/D1OB00298H, CommunicationXiao-Feng Wu, Ren-Rui Xu, wei wang, Jian-Li Liu, Xinxin QiAn efficient carbonylative procedure for the synthesis of 3-arylquinoin-2(1H)-ones has been established.

Copper(II)-Catalysed Direct C3-H Esterification of Indoles Assisted by an N,N-Bidentate Auxiliary Moiety

Org. Biomol. Chem., 2021, Accepted ManuscriptDOI: 10.1039/D0OB02301A, PaperYou-lu Pan, Jianzhong Chen, Gangjian Li, Haifeng Xu, Hu Xu-yangThe regioselective direct C3-esterification of indoles with OXA is developed in the efficient reaction with carboxylic acid using catalyst CuBr2 and oxidants Ag2CO3 and K2S2O8. The simple experimental procedure is...The content of this RSS Feed (c) The Royal Society of Chemistry

Recent Advances in the Synthesis and Reactivity of Azetidines: Strain-Driven Character of the Four-Membered Heterocycle

Org. Biomol. Chem., 2021, Accepted ManuscriptDOI: 10.1039/D1OB00061F, Review ArticleHaseeb Mughal, Michal SzostakAzetidines represent one of the most important four-membered heterocycles used in organic synthesis and medicinal chemistry. The reactivity of azetidines is driven by a considerable ring strain, while at the...The content of this RSS Feed (c) The Royal Society of Chemistry

Divergent Chiron Approach for the First Total Synthesis of (+)-Pseudonocardide A, (+)-Pseudonocardide C and an epimer of ent-Pseudonocardide D

Org. Biomol. Chem., 2021, Accepted ManuscriptDOI: 10.1039/D1OB00042J, PaperKapil Sharma, Naresh Surineni, Sayani Das, Shivajirao L. GholapA concise and divergent chiron approach for the first total synthesis of (+)-Pseudonocardide A, (+)-Pseudonocardide C and an epimer of ent-Pseudonocardide D is reported starting from D-ribose. The salient features...The content of this RSS Feed (c) The Royal Society of Chemistry

Synthesis and characterization of mono S-lipidated peptide hydrogels: a platform for the preparation of reactive oxygen species responsive materials

Org. Biomol. Chem., 2021, Accepted ManuscriptDOI: 10.1039/D1OB00355K, PaperAakanksha Rani, Luis Manuel M De Leon Rodriguez, Iman Kavianinia, Duncan James McGillivray, David Edward Williams, Margaret A BrimbleIn this work we report the synthesis of mono lipidated peptides containing a 3-mercaptopropionate linker in the N-terminus by means of a photoinitiated thiol-ene reaction (S-lipidation).

Rh-catalyzed C-H Alkylation Enabling Modular Synthesis of CF3-substituted Benzannulated Macrocyclic Inhibitors of B cell responses

Org. Biomol. Chem., 2021, Accepted ManuscriptDOI: 10.1039/D1OB00296A, CommunicationTao Sun, Shijun He, Zhongliang Xu, Jian-Ping Zuo, Yang Yu, Weibo YangInspired by Aspirin and Chalcone, herein, we describe a modular biomimetic strategy to achieve a new class of CF3-bearing benzannulated macrolactams. Key to the success of macrolactams was the utilization...The content of this RSS Feed (c) The Royal Society of Chemistry

Phosphorus Containing Porous Organic Polymers: Synthetic Techniques and Applications in Organic Synthesis and Catalysis

Org. Biomol. Chem., 2021, Accepted ManuscriptDOI: 10.1039/D1OB00137J, Review ArticlePramod Kumar, Animesh Das, Biplab MajiThe phosphorous-containing porous organic polymer is a trending material for the synthesis of heterogeneous catalysts. Decades of investigations have established phosphines as versatile ligands in homogeneous catalysis. Recently, phosphine-based heterogeneous...The content of this RSS Feed (c) The Royal Society of Chemistry

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