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Lewis Acid Mediated Cyclization: Synthesis of 2-Spirocyclohexylindolines Bearing Vicinal Quaternary Carbons

Org. Biomol. Chem., 2021, Accepted ManuscriptDOI: 10.1039/D1OB00293G, CommunicationHongbin Zhang, Wen Chen, Xiangkai Kong, Zhimin Xiong, Xiang Zhi, Xueling Meng, Jingfeng ZhaoHerein, we report the synthesis of 2-spirocyclohexylindolines based on a Lewis acid mediated cyclization.

Studies on Chemoselective Synthesis of 1,4- and 1,2-Dihydropyridine Derivatives by Hantzsch-Like Reaction: A Combined Experimental and DFT Study

Org. Biomol. Chem., 2021, Accepted ManuscriptDOI: 10.1039/D0OB02289F, PaperPeng Li, Shijie Wang, Nana Tian, Hong Yan, Juan Wang, Xiuqing SongIn the experimental process of preparing diethyl 3,5-dicarboxylate-1,4-dihydropyridine (1,4-DHP) by Hantzsch-Like reaction, it was found that a by-product named diethyl 3,5-dicarboxylate-1,2-dihydropyridine (1,2-DHP) were produced along with the reaction.

Selective sensing of adenosine monophosphate (AMP) over adenosine diphosphate (ADP), adenosine triphosphate (ATP), and inorganic phosphates with zinc(II)-dipicolylamine-containing gold nanoparticles

Org. Biomol. Chem., 2021, Accepted ManuscriptDOI: 10.1039/D1OB00341K, PaperLena Reinke, Marcus Koch, Christine Müller-Renno, Stefan KubikMixed monolayer-protected gold nanoparticles containing surface-bound triethylene glycol and dipicolylamine groups aggregated in water/methanol, 1:2 (v/v) in the presence of nucleotides, if the solution also contained zinc(II) nitrate to convert...The content of this RSS Feed (c) The Royal Society of Chemistry

Recent Advances in the Synthesis of Pyrido[1,2-a]indoles

Org. Biomol. Chem., 2021, Accepted ManuscriptDOI: 10.1039/D1OB00153A, Review ArticleYunxin Yao, Mouad Alami, Abdallah Hamze, Olivier ProvotThe pyrido[1,2-a]indole unit found in many organic compounds such as natural products, pharmaceuticals, and materials, has intensively stimulated the research of new synthetic pathways giving access to this heterocyclic nucleus...The content of this RSS Feed (c) The Royal Society of Chemistry

Molecular probes for selective detection of cysteine cathepsins

Org. Biomol. Chem., 2021, Accepted ManuscriptDOI: 10.1039/D1OB00225B, Review ArticleKelton A Schleyer, Lina CuiCysteine cathepsins are proteases critical in physiopathological processes and show potential as targets or biomarkers for diseases and medical conditions. The 11 members of the cathepsin family are redundant in...The content of this RSS Feed (c) The Royal Society of Chemistry

Metal Free Tandem Reactions of 1-(2-iodoaryl)-2-yn-1-ones with Sodium Azide for the Synthesis of 2,1-Benzoisoxazole Containing 1,2,3-Triazoles

Org. Biomol. Chem., 2021, Accepted ManuscriptDOI: 10.1039/D0OB02608E, PaperKashif Majeed, Fengtao Zhou, Qiuyu ZhangA metal free approach has been developed for the synthesis of benzo[c]isoxazole (anthranils) containing 1,2,3-triazoles. The reaction proceeded efficiently through a [3+2]azide-alkyne cycloaddition, SNAr azidation and denitrogenative cyclization sequences. The...The content of this RSS Feed (c) The Royal Society of Chemistry

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