Robust Buchwald–Hartwig amination enabled by ball-milling

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Org. Biomol. Chem., 2019, 17,1722-1726DOI: 10.1039/C8OB01781F, Communication Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Qun Cao, William I. Nicholson, Andrew C. Jones, Duncan L. BrowneAn operationally simple mechanochemical method for the Pd catalysed Buchwald–Hartwig amination of arylhalides with secondary amines has been developed using a Pd PEPPSI catalyst system.The content of this RSS Feed (c) The Royal Society of Chemistry

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