An organocatalytic asymmetric Mannich reaction of pyrazoleamides with cyclic trifluoromethyl ketimines: enantioselective access to dihydroquinazolinone skeletons

Org. Biomol. Chem., 2018, 16,3372-3375DOI: 10.1039/C8OB00707A, CommunicationYuan Luo, Ke-Xin Xie, Deng-Feng Yue, Xiao-Mei Zhang, Xiao-Ying Xu, Wei-Cheng YuanA series of trifluoromethyl dihydroquinazolinones were obtained in excellent results via an asymmetric Mannich reaction of pyrazoleamides and cyclic trifluoromethyl ketimines.The content of this RSS Feed (c) The Royal Society of Chemistry

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