NMR analyses on N-hydroxymethylated nucleobases - implications for formaldehyde toxicity and nucleic acid demethylases

Org. Biomol. Chem., 2018, Advance ArticleDOI: 10.1039/C8OB00734A, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.S. Shishodia, D. Zhang, A. H. El-Sagheer, T. Brown, T. D. W. Claridge, C. J. Schofield, R. J. HopkinsonNMR studies reveal that formaldehyde, a toxic pollutant and metabolite, reacts with nucleotides to form N-hydroxymethylated adducts of varying stabilities.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

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