Lewis Acid Mediated Cyclization: Synthesis of 2-Spirocyclohexylindolines Bearing Vicinal Quaternary Carbons

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Org. Biomol. Chem., 2021, Accepted ManuscriptDOI: 10.1039/D1OB00293G, CommunicationHongbin Zhang, Wen Chen, Xiangkai Kong, Zhimin Xiong, Xiang Zhi, Xueling Meng, Jingfeng ZhaoHerein, we report the synthesis of 2-spirocyclohexylindolines based on a Lewis acid mediated cyclization. This diastereoselective procedure provides the target structrues in a straightforward way via dual activation.The content of this RSS Feed (c) The Royal Society of Chemistry

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