Enzymatic synthesis of base-modified RNA by T7 RNA polymerase. A systematic study and comparison of 5-substituted pyrimidine and 7-substituted 7-deazapurine nucleoside triphosphates as substrates

Org. Biomol. Chem., 2018, Accepted ManuscriptDOI: 10.1039/C8OB01498A, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Nemanja Milisavljevic, Pavla Perlikova, Radek Pohl, Michal HocekWe synthesized a small library of eighteen 5-substituted pyrimidine or 7-substituted 7-deazapurine nucleoside triphosphates bearing methyl, ethynyl, phenyl, benzofuryl or dibenzofuryl groups through cross-coupling reactions of nucleosides followed by triphosphorylation...The content of this RSS Feed (c) The Royal Society of Chemistry

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