Directed Nickel-Catalyzed 1,2-Dialkylation of Alkenyl Carbonyl Compounds

Chem. Sci., 2018, Accepted ManuscriptDOI: 10.1039/C8SC01735B, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Joseph Derosa, Vincent A van der Puyl, Van T Tran, Mingyu Liu, Keary M. EngleA nickel-catalyzed conjunctive cross-coupling of non-conjugated alkenes, alkyl halides, and alkylzinc reagents is reported. Regioselectivity is controlled by chelation of a removable bidentate 8-aminoquinoline directing group. Under optimized conditions, a...The content of this RSS Feed (c) The Royal Society of Chemistry

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