Difluorination of ?-(Bromomethyl)styrenes via I(I)/I(III) Catalysis: Facile Access to Electrophilic Linchpins for Drug Discovery

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Chem. Sci., 2021, Accepted ManuscriptDOI: 10.1039/D1SC01132D, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Joel Häfliger, Keith Livingstone, Constantin Daniliuc, Ryan GilmourSimple ?-(bromomethyl)styrenes can be processed to a variety of 1,1-difluorinated electrophilic building blocks via I(I)/I(III) catalysis. This inexpensive main group catalysis strategy employs p-TolI as an effective organocatalyst when combined...The content of this RSS Feed (c) The Royal Society of Chemistry

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