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Cyclization of interlocked fumaramides into ?-lactams: experimental and computational mechanistic assessment of the key intercomponent proton transfer and the stereocontrolling active pocket

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Posted January 21st, 2021 by admin

Chem. Sci., 2021, 12,747-756DOI: 10.1039/D0SC05757F, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Alberto Martinez-Cuezva, Aurelia Pastor, Marta Marin-Luna, Carmen Diaz-Marin, Delia Bautista, Mateo Alajarin, Jose BernaA mechanistic study of the diastereoselective cyclization of interlocked fumaramides to give ?-lactams unveils the key factors for successfully taming the process.The content of this RSS Feed (c) The Royal Society of Chemistry

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