Biomimetic nanochannels for the discrimination of sialylated glycans via a tug-of-war between glycan binding and polymer shrinkage

Chem. Sci., 2020, 11,748-756DOI: 10.1039/C9SC05319K, Edge Article Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Minmin Li, Yuting Xiong, Dongdong Wang, Yunhai Liu, Bing Na, Haijuan Qin, Jinxuan Liu, Xinmiao Liang, Guangyan QingA glycan-responsive polymer-modified nanochannels system enables the precise discrimination of sialylated glycan linkage isomers via the different “OFF–ON” changes resulting from a “tug-of-war” between polymer-glycan binding and polymer shrinkage.The content of this RSS Feed (c) The Royal Society of Chemistry

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