2-Substituted 2'-Deoxyinosine 5'-Triphosphates as Substrates for Polymerase Synthesis of Minor-Groove-Modified DNA and Effects on Restriction Endonuclease Cleavage

Org. Biomol. Chem., 2019, Accepted ManuscriptDOI: 10.1039/C9OB02502B, PaperJan Matyasovsky, Michal HocekFive 2-substituted 2'-deoxyinosine triphosphates (dRITP) were synthesized and tested as substrates in enzymatic synthesis of minor-groove base-modified DNA. Only 2-methyl and 2-vinyl derivatives proved to be good substrates for Therminator...The content of this RSS Feed (c) The Royal Society of Chemistry

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