Cyanidin-3-O-glucoside inhibits A?40 fibrillogenesis, disintegrates preformed fibrils, and reduces amyloid cytotoxicity

Food Funct., 2020, Accepted ManuscriptDOI: 10.1039/C9FO00316A, PaperFu-Feng Liu, Fang Zhao, Wenjuan Wang, Jingcheng Sang, Longgang Jia, Li Li, Fuping LuAlzheimer's disease (AD) is mainly caused by the fibrillogenesis of amyloid-? protein (A?). Therefore, development of effective inhibitors against A? fibrillogenesis offers great hope for the treatment of AD. Cyanidin-3-O-glucoside...The content of this RSS Feed (c) The Royal Society of Chemistry

Genistein inhibits high-fat-induced obesity through miR-222 by targeting BTG2 and adipor1

Food Funct., 2020, Accepted ManuscriptDOI: 10.1039/C9FO00861F, PaperMailin Gan, Linyuan Shen, Shujie Wang, Zhixian Guo, Ting Zheng, Yuan Fan, Ya Tan, Lin Liu, Lei Chen, Anan Jiang, Xuewei Li, Shunhua Zhang, Li zhuObesity and diabetes mellitus have become major health problems worldwide. In recent years, genistein has been found to be capable of inhibiting obesity and alleviating insulin resistance.

The effects of caloric restriction and its mimetics in Alzheimer's disease through autophagy pathways

Food Funct., 2020, Accepted ManuscriptDOI: 10.1039/C9FO02611H, Review ArticleYi Yang, Lihui ZhangAlzheimer's disease (AD) is a neurodegenerative disorder that commonly occurs among older individuals. Increasing evidence suggests that a low-caloric diet might be a promising adjuvant therapeutic strategy for slowing or...The content of this RSS Feed (c) The Royal Society of Chemistry

Adhesion and anti-inflammatory potential of Lactobacillus rhamnosus GG in sea buckthorn based beverage matrix

Food Funct., 2020, Accepted ManuscriptDOI: 10.1039/C9FO02249J, Papersrijita sireswar, Sutapa Biswas, Gargi DeyTConsumption of probiotic based foods due to their health promoting effects have increased over the years. Hence, the application platforms of the food industries have directed their efforts in development...The content of this RSS Feed (c) The Royal Society of Chemistry

The adsorption and oxidation of SO2 on MgO surface: Experimental and DFT calculation studies

Environ. Sci.: Nano, 2020, Accepted ManuscriptDOI: 10.1039/C9EN01474H, PaperHonghong Wang, Cheng Zhong, Qingxin Ma, Jinzhu Ma, Hong HeThe heterogeneous oxidation of sulfur dioxide (SO2) to sulfate on the surface of MgO particles was investigated by in situ di?use re?ectance infrared Fourier transform spectroscopy (DRIFTS) and Density Functional...The content of this RSS Feed (c) The Royal Society of Chemistry

External oxidant-free alkylation of quinoline and pyridine derivatives

Org. Biomol. Chem., 2020, Accepted ManuscriptDOI: 10.1039/C9OB02653C, CommunicationLinhua Shen, Xianying Gao, Nannan Luan, Zhenwei Liu, Jingya Li, Dapeng Zou, Yangjie Wu, Yusheng WuA novel and efficient method for the generation of alkyl radicals and the alkylation of quinoline and pyridine derivatives at mild conditions has been developed. This strategy allows the direct...The content of this RSS Feed (c) The Royal Society of Chemistry

Concise synthesis of thiophene C-nucleoside analogues bearing sugar residue and aromatic residue through dimerization and sulfur heterocyclization of sugar alkynes and substituted iodoethynylbenzene

Org. Biomol. Chem., 2020, Accepted ManuscriptDOI: 10.1039/C9OB02717C, PaperXiang Zhou, Tongtong Jia, Yang Luo, Hong Liu, Fuyi Zhang, YuFen ZhaoThe synthesis of thiophene C-nucleoside analogues bearing sugar residue (mono- and disaccharides) and aromatic residue has been achieved by symmetric dimerization of terminal sugar alkynes or unsymmetric dimerization of terminal...The content of this RSS Feed (c) The Royal Society of Chemistry

Synthesis of ?-functionalized ketones by visible-light promoted oxygenation of alkenes

Org. Biomol. Chem., 2020, Accepted ManuscriptDOI: 10.1039/C9OB02754H, Review ArticleXinchi Gong, Chunyin Zhu, Long-Wu YeThis article gives a short review on the visible-light promoted synthesis of ?-substituted ketones from alkenes. Various ?-substituted ketones, including ?-halo, sulfinyl/sulfonyl, aryl, azido and thiocyanato ketones can be synthesized...The content of this RSS Feed (c) The Royal Society of Chemistry

Coronavirus: No change in outbreak despite China spike, WHO says

The World Health Organization says it is "not seeing a dramatic increase" in cases outside China.

No Time To Die: The verdict on Billie Eilish's James Bond theme

The verdict on the teenager's ballad for Daniel Craig's final outing as 007, which she released overnight.

NASA's Four Possible Planetary Missions Stretch Across the Solar System

These missions travel to Venus, Io, and Neptune's Triton—but only two will be selected.

Rutter's store chain discloses security breach involving POS malware

Security breach impacts locations in Pennsylvania and West Virginia.

Ohio man arrested for running Bitcoin mixing service that laundered $300 million

This is the first case the DOJ has brought against a Bitcoin mixer.

Services Australia spent AU$130m on contractors chasing robo-debts

The department used labour hire firms to track down debts it believed were due to be paid back by those in receipt of welfare.

William Barr: Trump tweets make my job 'impossible'

US Attorney General William Barr said he would not be bullied by anyone, including the president.

Google ordered to reveal author of Australian dentist's bad review

The Australian court ruling forces the US firm to hand over details about the anonymous poster.

Quiz of the week: On the Oscars, Storm Ciara and iPhones

Have you been paying attention to what's been going on during the past seven days?

Africa's week in pictures: 7-13 February 2020

A selection of the best photos from across the continent and beyond this week.

Karachi groom chased from wedding after first wife turns up

A banquet descends into violence in Pakistan after the groom is revealed to have two other wives.

Indonesia's Jokowi: Reformer turns pragmatist

Joko Widodo swept into power promising to change Indonesia - but the journey hasn't been smooth.

'If you press the paw you will hear the heartbeat'

After John's Reid's son died, his organs were donated and now the recipient has thanked him in the sweetest way.

Why were two Mexican butterfly activists found dead?

Relatives and co-workers live in fear after two monarch butterfly activists were found dead in Mexico.

Coronavirus: Why have two reporters in Wuhan disappeared?

They said they wanted to provide the "truth" about the coronavirus outbreak. Now they cannot be found.

7-month-old Simsim secures $16M for its social commerce in India

Simsim, a social commerce startup in India, said on Friday it has raised $16 million in seven months of its existence as it attempts to replicate the offline retail experience in the digital world with help from influencers.

Sanctuary counties: Inside America's gun rights resistance

Democrats swept to victory in Virginia after campaigning on stricter gun control. Weeks later, the backlash began.

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