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Nordic airline averts business disaster with application performance monitoring

Following an emergency decision to move to Amazon Web Services, Iceland’s Wow Air has wholeheartedly bought into the cloud

Nordic airline averts business disaster with application performance monitoring

Following an emergency decision to move to Amazon Web Services, Iceland’s Wow Air has wholeheartedly bought into the cloud

Nordic airline averts business disaster with application performance monitoring

Following an emergency decision to move to Amazon Web Services, Iceland’s Wow Air has wholeheartedly bought into the cloud

A Formal Intermolecular [4+2] Cycloaddition Reaction of 1,3-Disubstituted Indoles and Alkylquinone

Org. Biomol. Chem., 2017, Accepted ManuscriptDOI: 10.1039/C7OB00392G, PaperChao Lin, Hong-Jin Du, Hui Zhao, Ding-Fei Yan, Nai-Xin Liu, Hong-Bin Sun, Xiaoan Wen, Qing-Long XuA formal [4+2] cycloaddition reaction of 1,3-disbstituted indoles and alkylquinone was realized to furnish polycyclic indolines in good yields.

Discovery and Optimization of Selective Inhibitors of Protein Arginine Methyltransferase 5 by Docking-Based Virtual Screening

Org. Biomol. Chem., 2017, Accepted ManuscriptDOI: 10.1039/C7OB00070G, Paperyan ye, Bidong Zhang, Ruifeng Mao, Chenhua Zhang, Yulan Wang, Jing Xing, Yu-Chih Liu, Xiaomin Luo, Hong Ding, Yaxi Yang, Bing Zhou, Hualiang Jiang, Kaixian Chen, Cheng Luo, Mingyue ZhengProtein arginine methyltransferase-5 (PRMT5) is a type II PRMT enzyme critical for diverse cellular processes and different types of cancers.

Metal-free enantioselective addition of nucleophilic silicon to aromatic aldehydes catalyzed by a [2.2]paracyclophane-based N-heterocyclic carbene catalyst

Org. Biomol. Chem., 2017, Accepted ManuscriptDOI: 10.1039/C7OB00243B, CommunicationPing An, Yuwen Huo, Zhen Chen, Chun Song, Yudao MaThe first example of transition metal-free enantioselective 1,2-silylation of aromatic aldehydes is reported. This protocol enables an easy access to chiral ?-hydroxysilanes from readily available aromatic aldehydes.The content of this RSS Feed (c) The Royal Society of Chemistry

Recent Advances in Controlling the Internal and External Properties of Self-Assembling Cyclic Peptide Nanotubes and Dimers

Org. Biomol. Chem., 2017, Accepted ManuscriptDOI: 10.1039/C7OB00351J, Review ArticleNuria Rodriguez-Vazquez, Manuel Amorin, Juan R GranjaOne of the most powerful strategies for the preparation of nanotubes is based on the stacking of flat-shaped cyclic peptide components. This strategy allows precise control of the nanotube internal...The content of this RSS Feed (c) The Royal Society of Chemistry

Novel chemoenzymatic oxidation of amines into oximes based on hydrolase-catalysed peracid formation

Org. Biomol. Chem., 2017, Accepted ManuscriptDOI: 10.1039/C7OB00374A, CommunicationDaniel Mendez-Sanchez, Ivan Lavandera, Vicente Gotor, Vicente Gotor-FernandezThe efficient transformation of benzylamines into the corresponding oximes has been described by means of a chemoenzymatic process. This strategy is based on a two-step sequence developed in one-pot at...The content of this RSS Feed (c) The Royal Society of Chemistry

A Fluorescein-Based Chemosensor for Relay Fluorescence Recognition of Cu(II) Ions and Biothiols in Water and its Applications to Molecular Logic Gates and Living Cell Imaging

Org. Biomol. Chem., 2017, Accepted ManuscriptDOI: 10.1039/C7OB00525C, PaperZhen-Hai Fu, Lu-Bin Yan, Xiaolong Zhang, Fan-Fan Zhu, Xin-Long Han, Jianguo Fang, Ya-Wen Wang, Yu PengRelay recognition of copper(II) ions and biothiols via a fluorescence "on-off-on" cascade was designed and realized as a new sequential combination of cation and small molecule. Probe 1 bearing a...The content of this RSS Feed (c) The Royal Society of Chemistry

Francois Fillon's wife Penelope under formal investigation

The French presidential candidate's wife is accused of being paid public money for a "fake job".

Ivory Coast's former first lady Simone Gbagbo acquitted

Crimes against humanity charges relate to the deadly violence after the 2010 presidential elections.

France 0-2 Spain

Video technology is used to reverse two incorrect decisions as Spain beat France in a friendly in Paris.

UK PM signs letter that will trigger Brexit

The letter will be delivered to the EU on Wednesday, marking formal notice of the UK's exit.

Trump signs order undoing Obama climate change policies

Environmentalists warn Mr Trump's order will have serious consequences at home and abroad.

Russia arrest 'like a bad dream'

Olga Lozina featured in an iconic photo taken during an anti-government protest in Moscow on Sunday.

Republic of Ireland 0-1 Iceland

The Republic of Ireland's 15-game unbeaten run at the Aviva Stadium ends as their under-strength side are beaten by Iceland.

Nanoimprinting-induced molecular orientation in poly(3-hexylthiophene) nanogratings and its miraculous eternal after thermal annealing

Polym. Chem., 2017, Accepted ManuscriptDOI: 10.1039/C7PY00378A, PaperGuangzhu Ding, Kaixuan Wang, xiaohui Li, chao Wang, Zhijun Hu, Jieping LiuNanoimprinting has been well explored not only to fabricate topographical nanostructures simply, but also to induce the preferential molecule orientation of conjugated polymer film. We demonstrate here that the nanograting...The content of this RSS Feed (c) The Royal Society of Chemistry

A Dendrimer-Hydrophobic Interaction Synergy Improves the Stability of Polyion Complex Micelles

Polym. Chem., 2017, Accepted ManuscriptDOI: 10.1039/C7PY00304H, PaperMarcos Fernandez-Villamarin, Ana Sousa-Herves, Silvia Porto, Noelia Guldris, Jose Martinez-Costas, Ricardo Riguera, Eduardo Fernandez-MegiaPolyion complex (PIC) micelles incorporating PEG-dendritic copolymers display an unprecedented stability towards ionic strength that is amplified via hydrophobic interactions.

Highly Porous Photoluminescent Diazaborole-Linked Polymers: Synthesis, Characterization, and Application to Selective Gas Adsorption

Polym. Chem., 2017, Accepted ManuscriptDOI: 10.1039/C6PY02156E, PaperZafer Kahveci, Ali Kemal Sekizkardes, Ravi K K. Arvapally, Logan Wilder, Hani M. El-KaderiThe formation of boron-nitrogen (B-N) bonds has been widely explored for the synthesis of small molecules, oligomers, or linear polymers; however, its use in constructing porous organic frameworks remains very...The content of this RSS Feed (c) The Royal Society of Chemistry

Polyamino acid-based gemcitabine nanocarriers for targeted intracellular drug delivery

Polym. Chem., 2017, Accepted ManuscriptDOI: 10.1039/C7PY00443E, PaperWenzhuo Teng, Fan Jia, Haijie Han, Zhihui Qin, Qiao Jin, Jian JiIn the present study, we have successfully fabricated a biocompatible polyamino acid-based nanocarrier with reduction-sensitivity and targeting ability for gemcitabine (GEM) delivery.

Polyurethane based organic macromolecular contrast agent (PU-ORCA) for magnetic resonance imaging

Polym. Chem., 2017, Accepted ManuscriptDOI: 10.1039/C7PY00166E, PaperHaritz Sardon, Sofiem Garmendia, Daniele Mantione, Silvia Alonso-de Castro, Coralie Jehanno, Luis Lezama, James Hedrick, David Mecerreyes, Luca SalassaMagnetic resonance imaging (MRI) is one of the leading imaging modalities because of the combination of convenient non-invasive application, high spatial resolution, and tomographic capability.

A Mechanistic Investigation of Pickering Emulsion Polymerization

Polym. Chem., 2017, Accepted ManuscriptDOI: 10.1039/C7PY00308K, PaperAndrea Lotierzo, Stefan A. F. BonPickering emulsion polymerization offers a versatile way of synthetising hybrid core-shell latexes where a polymer core is surrounded by an armour of inorganic nanoparticles. A mechanistic understanding of the polymerization...The content of this RSS Feed (c) The Royal Society of Chemistry

RAFT/MADIX polymerization of N-vinylcaprolactam in water-ethanol solvent mixtures

Polym. Chem., 2017, Accepted ManuscriptDOI: 10.1039/C6PY02224C, CommunicationIne Van Nieuwenhove, Samarendra Maji, Mamoni Dash, Sandra Van Vlierberghe, Richard Hoogenboom, Peter DubruelThe present paper demonstrates the successful RAFT/MADIX polymerization of N-vinylcaprolactam at ambient temperature in water-ethanol mixtures.

Exploring structural effects in single-chain "folding" mediated by intramolecular thermal Diels-Alder chemistry

Polym. Chem., 2017, Accepted ManuscriptDOI: 10.1039/C7PY00320J, PaperAshley Hanlon, Ian Martin, Elizabeth Bright, Jennifer Chouinard, Kyle Rodriguez, Gabriel Patenotte, Erik B BerdaWe describe a method to fold single polymer chains into nanoparticles using simple thermal Diels-Alder (DA) chemistry.

Oleuropein down-regulated IL-1[small beta]-induced inflammation and oxidative stress in human synovial fibroblasts cell line SW982.

Food Funct., 2017, Accepted ManuscriptDOI: 10.1039/C7FO00210F, PaperMaria Luisa Castejon, Maria Angeles Rosillo, Tatiana Montoya, Alejandro Gonzalez-Benjumea, Jose G Fernandez-Bolanos, Catalina Alarcon-de-la-LastraRheumatoid arthritis (RA) is a chronic and systemic inflammatory autoimmune disease mainly characterized by aggressive hyperproliferation of synovial fibroblasts (SFs) and massive infiltration of inflammatory immune cells inducing a progressive...The content of this RSS Feed (c) The Royal Society of Chemistry

Effect of Isabel grape addition on the physicochemical, microbiological and sensory characteristics of probiotic goat milk yogurt

Food Funct., 2017, Accepted ManuscriptDOI: 10.1039/C6FO01795A, PaperFrancyeli Araujo Silva, Maria Elieidy Gomes Oliveira, Karol Brito Sampaio, EVANDRO LEITE DE SOUZA, Rossana Feitosa Figueiredo, Carlos Eduardo Vasconcelos Oliveira, Manuela Pintado, Rita Cassia QueirogaThe goat milk is an attractive food because of its nutritional properties, easy digestibility and hypoallergenicity.

Efficient Catalytic Greenhouse Gas-Free Hydrogen and Aldehyde Formation from Aqueous Alcohol Solutions

Energy Environ. Sci., 2017, Accepted ManuscriptDOI: 10.1039/C6EE03739A, CommunicationTracy L Lohr, Aidan Mouat, Neil M Schweitzer, Peter C Stair, Massimiliano Delferro, Tobin MarksHydrogen is an ideal fuel candidate due to its clean combustion characteristics.

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